Mutation panel described for screening BRCA1/2 mutations in French Canadians.

Life Science Weekly | December 28, 2004 | Copyright

2004 DEC 28 - (NewsRx.com & NewsRx.net) -- Researchers with the Montreal General Hospital reported in 1998 "that a significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor specific germline mutations in BRCA1 or BRCA2 attributed to common founders."

Now, in a paper in the International Journal of Cancer, the team has determined "the frequency of previously described mutations (n=7) and 13 mutations identified in French Canadian families since 1998, in a new group of families (n=88)."

K.K. Oros and colleagues ...

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