Energy availability and alcohol-related liver pathology. From: Alcohol Research & Health | Date: December 22, 2003| Author: Cunningham, Carol C.; Van Horn, Cynthia G. | COPYRIGHT 2003 U.S. Government Printing Office. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

Alcohol consumption alters the metabolism of the most common type of cell found in the liver, the hepatocyte. The presence of alcohol in the body causes the liver to use more oxygen--for example, when breaking down the alcohol. Increased oxygen use, in turn, causes oxygen deficits in several key cells, particularly in hepatocytes located near the small hepatic veins. These veins return blood to the heart for re-oxygenation after it has passed through the liver. Hepatocytes surroundi...

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