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Asbestos exposure and antineutrophil cytoplasmic antibody (ANCA) positivity.

From: Archives of Environmental Health  |  Date: 10/1/2003  |  Author: Bartunkova, Jirina; Benakova, Hana; Fenclova, Zdenka; Hladikova, Marie; Lebedova, Jindriska; Pelclova, Daniela

The authors used indirect immunofluorescence to examine the association of antineutrophil cytoplasmic antibodies (ANCAs) with exposure to asbestos among 61 asbestos-exposed patients (mean exposure = 24.6 yr) and 39 nonexposed controls. ANCA positivity was detected significantly more frequently (p = 0.034) in the asbestos-exposed group (21.3%) than in the control group (5.1%). ANCA-associated diseases did not occur more frequently among subjects exposed previously to asbestos than among ...

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