Fluoroquinolone resistance in penicillin-resistant Streptococcus pneumoniae Clones, Spain.(Research) From: Emerging Infectious Diseases | Date: October 1, 2004| Author: Ardanuy, Carmen; Balsalobre, Luz; de la Campa, Adela G.; Fenoll, Asuncion; Linarez, Josefina; Perez-Trallero, Emilio | COPYRIGHT 2004 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

Among 2,882 Streptococcus pneumoniae sent to the Spanish Reference Laboratory during 2002, 75 (2.6%) were ciprofloxacin-resistant. Resistance was associated with older patients (3.9% in adults and 7.2% in patients [greater than or equal to] 65 years of age), with isolation from noninvasive sites (4.3% vs. 1.0%), and with penicillin and macrolide resistance. Among 14 low-level resistant (MIC 4-8 [micro]g/mL) strains, 1 had a fluoroquinolone efflux phenotype, and 13 showed single Par...