Strain typing methods and molecular epidemiology of Pneumocystis pneumonia.(Perspectives)
From: Emerging Infectious Diseases
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Date: 10/1/2004
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Author: Beard, Charles Ben; Hauser, Philippe M.; Kovacs, Joseph A.; Lundgren, Bettina; Nevez, Gilles; Roux, Patricia; Unnasch, Thomas R.
Pneumocystis pneumonia (PCP) caused by the opportunistic fungal agent Pneumocystis jirovecii (formerly P. carinii) continues to cause illness and death in HIV-infected patients. In the absence of a culture system to isolate and maintain live organisms, efforts to type and characterize the organism have relied on polymerase chain reaction-based approaches. Studies using these methods have improved understanding of PCP epidemiology, shedding light on sources of infection, transmission ...
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