Genotyping, orientalis-like Yersinia pestis, and plague pandemics.(Research)
From: Emerging Infectious Diseases
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Date: 9/1/2004
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Author: Castex, Dominique; Chenal-Francisque, Viviane; Crubezy, Eric; Dang, La Vu; Drancourt, Michel; Fournier, Pierre-Edouard; Ogata, Hiroyuki; Raoult, Didier; Roux, Veronique; Tran-Hung, Lam
Three pandemics have been attributed to plague in the last 1,500 years. Yersinia pestis caused the third, and its DNA was found in human remains from the second. The Antiqua biovar of Y. pestis may have caused the first pandemic; the other two biovars, Medievalis and Orientalis, may have caused the second and third pandemics, respectively. To test this hypothesis, we designed an original genotyping system based on intergenic spacer sequencing called multiple spacer typing (MST). We ...
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