Molecular analysis of Plasmodium ovale variants.(Research)

From: Emerging Infectious Diseases | Date: July 1, 2004| Author: | Copyright information

Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (Pov 1-3) were found in each variant-type isolate, and two different SSUrRNA sequences (Poc 1-2) in each classic-type isolate. Pov 1-3 were closer to sequences previously found in the Cameroon and MAL/MAI isolates, whereas Poc 1-2 were closer to sequences previously found in two clones of ...

<97% with Pov 1-3) than to that of clone 26 or Poc 2 (98.2%-98.4% identity). The Ghana isolate was also grouped as classic-type (>