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Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor.
Obesity, Fitness & Wellness Week
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August 7, 2004
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2004 AUG 7 - (NewsRx.com & NewsRx.net) -- Researchers have found that a large protein, alsin, is a Rab5 and Rac1 guanine nucleotide exchange factor, and may play a role in a juvenile form of amyotrophic lateral sclerosis.
"ALS2 is the gene mutated in a recessive juvenile form of amyotrophic lateral sclerosis (ALS2). ALS2 encodes a large protein termed alsin, which contains a number of predicted cell signaling and protein trafficking sequence motifs," scientists in the United States report.
"To gain insight into the overall function of alsin and to begin to ...
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