Guanine nucleotide exchange protein involved in dendritic formation.

Drug Week | May 28, 2004 | Copyright

2004 MAY 28 - (NewsRx.com & NewsRx.net) -- Researchers report the somatodendritic localization of the mRNA for EFA6A, a guanine nucleotide exchange protein for ARF6, in the rat hippocampus and its involvement in dendritic formation.

"EFA6A is a guanine nucleotide exchange protein (GEP) that can specifically activate ADP-ribosylation factor 6 (ARF6) in vitro. A recent study has demonstrated that ARF6 is involved in the dendritic formation of developing hippocampal neurons. This study examined a potential role for EFA6A in hippocampal development in Wistar rats," ...

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