Monkeypox transmission and pathogenesis in prairie dogs.(Research) From: Emerging Infectious Diseases | Date: March 1, 2004| Author: Damon, Inger K.; Goldsmith, Cynthia S.; Guarner, Jeannette; Johnson, Bill J.; Paddock, Christopher D.; Regnery, Russell L.; Reynolds, Mary G.; Shieh, Wun-Ju; Zaki, Sherif R. | COPYRIGHT 2004 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

During May and June 2003, the first cluster of human monkeypox cases in the United States was reported. Most patients with this febrile vesicular rash illness presumably acquired the infection from prairie dogs. Monkeypox virus was demonstrated by using polymerase chain reaction in two prairie dogs in which pathologic studies showed necrotizing bronchopneumonia, conjunctivitis, and tongue ulceration. Immunohistochemical assays for orthopoxviruses demonstrated abundant viral antigen...