The expression of foreign genes in animal cells.

From: Chemistry and Industry | Date: September 16, 1991| Author: | Copyright information

By manipulating the genome of cells from animals and particularly from man, we can explore the complex regulation of gene expression in higher organisms

Recombinant DNA techniques allow genes to be cloned and expressed in a variety of different cells. In the early days of genetic engineering the host cell chosen was inevitably Escherichia coli, because of its rapid growth rate and simple nutritional requirements. However, bacterial protein synthesis differs from that of eukaryotic organisms in a number of ways. Consequently there can be problems if the protein of interest is ...

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