Escherichia coli producing CTX-M-2 [beta]-lactamase in Cattle, Japan.(Research) From: Emerging Infectious Diseases | Date: January 1, 2004| Author: | COPYRIGHT 2004 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

From November 2000 to June 2001, Escherichia coli strains producing CTX-M-2 [beta]-lactamase were isolated from 6 (1.5%) of 396 cattle fecal samples and 2 (0.7%) of 270 surface swabs of cattle carcasses in Japan. The [bla.sub.CTX-M-2] gene responsible for CTX-M-2 production was encoded on transferable plasmids, and the gene was transferred to E. coil CSH2 with a very high frequency (2 x [10.sup.-4] to 6 x [10.sup.-1] per donor cells) by conjugation. Random amplified polymorphic DNA analysis of nine isolates showed at least five different patterns. These findings suggest that ...

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