Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, Vietnam.(Dispatches)

From: Emerging Infectious Diseases | Date: December 1, 2003| Author: Lan, Nguyen Thi Ngoc; Lien, Hoang Thi Kim; Tung, Le B.; Borgdorff, Martien W.; Kremer, Kristin; van Soolingen, Dick | Copyright information

Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).

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