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Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, Vietnam.(Dispatches)
From:
Emerging Infectious Diseases
| Date:
December 1, 2003| Author:
Lan, Nguyen Thi Ngoc; Lien, Hoang Thi Kim; Tung, Le B.; Borgdorff, Martien W.; Kremer, Kristin; van Soolingen, Dick
| COPYRIGHT 2003 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group.Copyright information
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Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).
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