Chromosomes are "nibbled" before they fuse.

Genomics & Genetics Weekly | December 26, 2003 | Copyright

2003 DEC 26 - (NewsRx.com & NewsRx.net) -- Overturning 60 years of scientific presumption, new evidence from Johns Hopkins scientists shows that enzymes nibble away at chromosomes when the chromosomes' protective tips, called telomeres, get too short.

Much like the plastic tips on shoelaces, telomeres protect the ends of chromosomes. When telomeres get too short, cells usually die. If they don't, the unprotected ends drag the chromosomes through an ugly assortment of fusions that lead to rearrangements, deletions and insertions that scramble the cell's genetic ...

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