Sodium hydroxide renders prion protein sensitive to proteinase K.

Anti-Infectives Week | December 15, 2003 | Copyright

2003 DEC 15 - (NewsRx.com & NewsRx.net) -- Sodium hydroxide renders the prion protein PrP[superscript]Sc sensitive to proteinase K.

According to recent research published in the Journal of General Virology, "Sodium hydroxide (NaOH) solutions are widely used for the purification of contaminated equipment, as they are known to inactivate a variety of pathogens. However, information about their effect on agents causing transmissible spongiform encephalopathy (TSE) is sparse and contradictory."

"Scrapie hamster brain homogenate, containing the ...

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