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Drug eruptions: approaching the diagnosis of drug-induced skin diseases.

From: Journal of Drugs in Dermatology  |  Date: 6/1/2003  |  Author: Knowles, Sandra R.; Nigen, Simon; Shear, Neil H.

Abstract

Adverse drug reactions are a major problem in drug therapy, and cutaneous drug reactions account for a large proportion of all adverse drug reactions. Cutaneous drug reactions are also a challenging diagnostic problem since they can mimic a large variety of skin diseases, including viral exanthema, collagen vascular disease, neoplasia, bacterial infection, psoriasis, and autoimmune blistering disease, among others. Furthermore, determining that a particular medication ...

<10% 
Macules                  Erythematous          Erythematous 
 
Shape                       Regular              Regular 
Mucous membrane               No               Yes (milder) 
Recurrence                    Yes                  Yes 
Fever                         No                    No 
Severity                       +                    ++ 
Death                         No                    No 
Age                         Younger              Younger 
Sex                       Male><10%>
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