Yellow nail pigmentation following depakote therapy.(Case Reports)

From: Journal of Drugs in Dermatology | Date: October 1, 2003| Author: Buka, Robert; Hille, Rachel; McCormack, Patricia | Copyright information

Abstract

Two months after being started on Depakote[R] (divalproex sodium; Abbott Laboratories Inc., Abbott Park, Illinois), a 57-year-old female noticed the development of a transverse yellow band on all 20 proximal nails that eventually led to complete nail plate discoloration. Six to eight weeks after discontinuation of Depakote, normalization of her proximal nail plates was noted.

Other anticonvulsants such as phenytoin and lithium have been documented to...

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