SIEMENS DEBUTS BONSAI FLUORESCENCE OPTICAL IMAGING TECHNOLOGY. Biotech Equipment Update | October 1, 2003 | COPYRIGHT 2003 Worldwide Videotex. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information) Copyright

Siemens Medical Solutions, San Francisco, has introduced bonSAI, a fluorescence optical imaging technology that enables in vivo imaging of molecular processes. As part of Siemens' commitment to the advancement of molecular imaging, bonSAI is expected to have a profound impact on the way drugs are developed, and the way diseases are understood and treated.

"Fluorescence imaging techniques are of particular interest to drug discovery and development because of their low cost, versatility and high throughput capability," said Markus Rudin, head of the Analytical and ...

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

	Confocal Fluorescence Imaging of Photosensitized DNA Denaturation in Cell Nuclei¶ Magazine article from: Photochemistry and Photobiology ; ...bases in one strand. The transition (denaturation) from a doublestranded (ds) to a...some drugs. We report here that DNA denaturation can occur in situ in cell nuclei as...from those that were a result of DNA denaturation. We investigated the influence of...
	Reversible thermal denaturation of human FGF-1 induced by low concentrations of guanidine hydrochloride Magazine article from: Biophysical Journal ; ...to effects of irreversible thermal denaturation. Here we report the determination...scanning calorimetry (DSC). The thermal denaturation is demonstrated to be two-state and...agreement with values from isothermal GuHCl denaturation monitored by fluorescence and circular...
	Birefringence measurement of rapid structural changes during collagen denaturation Magazine article from: Photochemistry and Photobiology ; ...measured rate coefficients describing the denaturation are not predicted by previous studies of collagen denaturation induced by slower, lower-temperature...Two types of laserinduced collagen denaturation can be differentiated: thermal denaturation...
	Sample Number and Denaturation Time Are Crucial for the Accuracy of Capillary-Based LightCyclers Magazine article from: Clinical Chemistry ; ...real-time PCR protocol has a denaturation step of 0 s at 95 C during cycling...supposed that increasing the denaturation time to 5 s would allow completion...completely filled; increasing the denaturation time to 5 s without filling...
	Investigating Mechanisms of Collagen Thermal Denaturation by High Resolution Second-Harmonic Generation Imaging Magazine article from: Biophysical Journal ; ...and large areas, we found that the denaturation process responsible for forming the...occurs at a higher rate than the global denaturation process occurring throughout the tendon...fibril density shows that the global denaturation process occurs at a length scale smaller...
	Pressure Denaturation of Staphylococcal Nuclease Studied by Neutron Small-Angle Scattering and Molecular Simulation Magazine article from: Biophysical Journal ; ...primitive thermodynamic model for heat denaturation of proteins. This socalled liquid...this model fails to predict pressure denaturation of proteins. As pointed out by Kauzmann...of unfolding pathways for pressure denaturation is inherently different from those...
	Enzyme Kinetics above Denaturation Temperature: A Temperature-Jump/Stopped-Flow Apparatus Magazine article from: Biophysical Journal ; ...enzyme reactions that are faster than the denaturation process can be investigated above denaturation temperatures. In addition, the temperature...extremely high temperatures even above denaturation temperature if the rates of the reactions...
	Increasing the Net Charge and Decreasing the Hydrophobicity of Bovine Carbonic Anhydrase Decreases the Rate of Denaturation with Sodium Dodecyl Sulfate Magazine article from: Biophysical Journal ; ...ABSTRACT This study compares the rate of denaturation with sodium dodecyl sulfate (SDS...This study reports the kinetics of denaturation in solutions containing SDS of the...anhydrides; plotting these rates of denaturation as a function of the number of modifications...
	Protein Subunit Composition Effects on the Thermal Denaturation at Different Stages During the Soy Protein Isolate Processing and Gelation Profiles of Soy Protein Isolates Magazine article from: JAOCS, Journal of the American Oil Chemists' Society ; ...focussed on the evaluation of thermal denaturation at three different stages during soy...conglycinin (7S) protein subunits. Protein denaturation during SPI processing was monitored...reflects the requirement of protein denaturation and formation of intermolecular bonds...
	Pretransitional structural changes in the thermal denaturation of ribonuclease S and S protein Magazine article from: Biophysical Journal ; ...dissociation, whereas the second is a concerted denaturation/dissociation. The thermal denaturation of ribonuclease S and its fragment, the...analysis monitored different aspects of the denaturation simultaneously. The unfolding pathway...

For more facts and information, see all results

Find more facts and information related to the article "SIEMENS DEBUTS BONSAI FLUORESCENCE OPTICAL ..."