Adenine analogs may be differentiation therapy agents for acute myeloid leukemia.

Biotech Week | August 13, 2003 | Copyright

2003 AUG 13 - (NewsRx.com & NewsRx.net) -- Adenine analogs may be differentiation therapy agents for acute myeloid leukemia.

According to published research from Japan, "Although the frequency of complete remission in acute myeloid leukemia (AML) has increased, the median duration of such remission is only 9 - 15 months, even when remission is achieved by treatment with conventional cytotoxic antileukemic drugs.

"These results clearly call for improved therapies. AML is characterized by a differentiation block leading to the accumulation of immature cells. ...

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