Chronic low-dose aspirin therapy tied to GI bleeding. (No Safe Dose?). From: OB GYN News | Date: July 1, 2003| Author: Worcester, Sharon | COPYRIGHT 2003 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group.Copyright information

ORLANDO, FLA.--Long-term low-dose aspirin therapy is a risk factor for gastrointestinal bleeding, data from the Physicians' Health Study suggest.

The finding comes from a case-control study of 451 case patients and 1,804 control patients among the more than 22,000 physicians in the randomized, placebo-controlled Physicians' Health Study. Patients were divided into quartiles of total cumulative aspirin use based on the prescribed dose of one 325-mg tablet every other day:...