HRT, estrogen, and postmenopausal women: year-old WHI study continues to raise questions.(hormone replacement therapy)(Women's Health Initiatives)

Sports Medicine Reports | July 1, 2003| | Copyright

The Women's Health Initiatives (WHI) was halted 1 year ago, but fallout from this landmark study continues. The study was designed to identify the risks or benefits of estrogen plus progesterone vs placebo in healthy postmenopausal women. More than 16,000 women were randomized to a fixed dose of conjugated estrogen 0.625 mg plus medroxyprogesterone 2.5 mg daily. The second arm of the study randomized women who had undergone hysterectomy to conjugated estrogen alone vs placebo. The combination estrogen/progesterone wing of the study was halted prematurely and results published ...

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