Townsend Letter for Doctors and Patients

Chronic fatigue, aging, mitochondrial function and nutritional supplements.

Townsend Letter for Doctors and Patients | July 1, 2003 | Copyright

Abstract

Intractable fatigue is the most common complaint of patients seeking medical care, and in most patients it is a chronic condition that is not reversed by sleep or rest. Although fatigue is a complex phenomenon, it has been defined recently as a multi-component sensation. It is related to aging, decreased mitochondrial function and loss in the ability of mitochondria in cells to produce high-energy molecules for cellular functions. Also, it is known that oxidative damage to mitochondria, mainly from Reactive Oxygen Species or ROS, resulting in modifications in…

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