Effect on inflammatory response may be related to serum corticosterone levels.

Immunotherapy Weekly | May 28, 2003 | Copyright

2003 MAY 28 - (NewsRx.com & NewsRx.net) -- Nicotine-induced inflammatoty decreasing effect on passive skin Arthus reaction in paraventricular nucleus-lesioned rats may be related to serum corticosterone levels.

"To evaluate the relationship between nicotine and immunological inflammation, we investigated the effects of nicotine on plasma extravasation of the passive skin Arthus reaction, elicited 4 hr after sensitizing skin with antiserum, and serum corticosterone levels in rats.

"Pretreatment with a single subcutaneous injection of nicotine (0.4 or 0.8 ...

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