Serine proteases appear to modulate vascular function and angiogenesis.

Angiogenesis Weekly | May 9, 2003 | Copyright

2003 MAY 9 - (NewsRx.com & NewsRx.net) -- Serine proteases appear to modulate vascular function and angiogenesis.

"Many serine proteases play important regulatory roles in complex biological systems, but only a few have been linked directly with capillary morphogenesis and angiogenesis. Here we provide evidence that serine protease activities, independent of the plasminogen activation cascade, are required for microvascular endothelial cell reorganization and capillary morphogenesis in vitro," researchers in the United States report.

"A homology cloning ...

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