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hypertrophy

The Columbia Encyclopedia, Sixth Edition | Date: 2008

hypertrophy , enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g., in an athlete as a result of increased exercise) and also the enlargement of a uterus in pregnancy are caused by hypertrophy of muscle cells. In pathology the thickening of the heart muscle from overstrain, as in hypertension (high blood pressure), is the result of hypertrophy. An organ subjected to extra work (e.g., the one kidney left to function after surgical removal of the other) usually compensates by enlarging; in such cases hyperplasia, an increase in the number of cells, generally accompanies hypertrophy.

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The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press

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hyperplasia
The Columbia Encyclopedia, Sixth Edition : see hypertrophy . Read more
athlete's heart
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pathology
The Columbia Encyclopedia, Sixth Edition ... structure produced in any cell, organ, or part of the body by disease. The changes in tissue include degeneration, atrophy, hypertrophy, hyperplasia, and inflammation. The microscope is an important factor in detecting tissue changes, especially in the examination ... Read more

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