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chymotrypsin
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chymotrypsin
The Columbia Encyclopedia, Sixth Edition
chymotrypsin , proteolytic, or protein-digesting, enzyme active in the mammalian intestinal tract. It catalyzes the hydrolysis of proteins , degrading them into smaller molecules called peptides . Peptides are further split into free amino acids . Chymotrypsin is produced in the pancreas as the inactive, or zymogen, form chymotrypsinogen. Along with other digestive enzymes of the pancreas, chymotrypsinogen is carried in the pancreatic juice through the pancreatic duct into the duodenum. There chymotrypsinogen is activated by another enzyme, trypsin, and by molecules of active chymotrypsin. Partly because it was one of the first enzymes available commercially in crystalline form, chymotrypsin has been studied extensively.
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The Columbia Encyclopedia, Sixth Edition 2008
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The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press
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chymotrypsin
chymotrypsin A peptidase enzyme found in the small intestine that acts on the interior peptide bonds of proteins .
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chymotrypsin
chymotrypsin (ky-moh- trip -sin) n. a protein-digesting enzyme (see peptidase ). It is secreted by the pancreas in an inactive form, chymotrypsinogen, that is converted into chymotrypsin in the duodenum by the action of trypsin.
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chymotrypsin
chymotrypsin An enzyme involved in the digestion of proteins; secreted as the inactive precursor chymotrypsinogen in the pancreatic juice. It is activated by trypsin , and is an endopeptidase , with a different specificity from trypsin and pepsin .
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chymotrypsin
chymotrypsin An endopeptidase enzyme in pancreatic juice that is secreted into the duodenum. The enzyme is secreted as an inactive precursor, chymotrypsinogen, which is activated by another pancreatic protease, trypsin .
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endopeptidase
endopeptidase A protein-digesting enzyme that cleaves a polypeptide chain at specific sites between amino acids. For example, chymotrypsin cleaves the chain next to aromatic amino acids, such as phenylalanine; trypsin cleaves the chain next to basic amino acids...
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