Recently added articles from Leprosy Review:
Editor's choice September 2008.(global leprosy record)(Editorial)
Sep 01, 2008; Lockwood, Diana N.J. ... This issue starts with two editorials looking at contrasting aspects of the disease. Paul Fine has made a meticulous dissection of the latest reports on the global leprosy figures that were published in the Weekly Epidemiological Record on 15 August 2008. These figures are important ...
Leprosy's global statistics--still room for improvement.(Editorial)
Sep 01, 2008; Fine, Paul E.M. ... WHO's latest update on leprosy was published in the Weekly Epidemiological Record on 15th August, entitled: 'Global leprosy situation, beginning of 2008'. (1) The report is accessible on the web at www.who.int/wer .... Most readers of Leprosy Review are familiar with these updates, as the ...
Leprosy and human rights.(Editorial)
Sep 01, 2008; Soutar, Douglas ... On the 18th June the United Nations Human Rights Council unanimously adopted a resolution (A/HRC/8/L.18) on 'The elimination of discrimination against persons affected by leprosy and their family members.' (1) This historic resolution was sponsored by 59 member states and made specific ...
The biology of nerve injury in leprosy.(Clinical report)
Sep 01, 2008; Scollard, David M. ... Introduction Nerve injury is a central feature of the pathogenesis of leprosy, and the basic biological aspects have been reviewed in many textbooks. (1-3) Selected aspects of current research on this subject have also been the subject of recent reviews. (4,5) This review is ...
Erythema nodosum leprosum in Nepal: a retrospective study of clinical features and response to treatment with prednisolone or thalidomide.(Clinical report)
Sep 01, 2008; Feuth, M. ... Summary Introduction Erythema nodosum leprosum (ENL) is an inflammatory reaction, which may occur in the course of leprosy and may result in nerve function impairment and subsequent disability. Methods This retrospective study explores demographic and disease ...
Neuropathic pain in people treated for multibacillary leprosy more than ten years previously.(Clinical report)
Sep 01, 2008; Saunderson, Paul ... Summary Objectives To identify patients with typical symptoms of neuropathic pain in a well-defined cohort of multibacillary patients being followed up as part of a relapse study in Ethiopia; to identify risk factors for the development of neuropathic pain. Design 96 ...
Voluntary muscle testing and dynamometry in diagnosis of motor impairment in leprosy: a comparative study within the INFIR Cohort Study.(Clinical report)
Sep 01, 2008; Suresh, M. ... Summary Aim To evaluate hand muscle weakness detected through dynamometry as an indicator for change in motor nerve function detected by Voluntary Muscle Testing (VMT) of ulnar and median nerves. Design The research was carried out as part of the INFIR Cohort Study ...
Government health workers as implementers of prevention of disability measures: an assessment of a prevention of disability project in selected counties of Guizhou Province, Peoples' Republic of China.(Clinical report)
Sep 01, 2008; Jinlan, Li ... Summary Objective The purpose of this study was to assess the effectiveness of government health workers as agents for the prevention of disability. Design A prevention of disability (POD) project for people affected by leprosy was conducted in nine counties of ...
An 8-12 year follow-up of highly bacillated Indian leprosy patients treated with WHO multi-drug therapy.(Clinical report)
Sep 01, 2008; Desikan, Kothapalle Vedantha ... Summary Objectives To follow up highly bacillated leprosy patients for a long period after release from treatment (RFT) and to look out for possibility of relapses. Results 660 patients with an initial bacterial positivity of 4 + , 5 + or 6 + who had undergone WHO ...
Activation of complement by Mycobacterium leprae requires disruption of the bacilli.(SHORT REPORT)(Clinical report)
Sep 01, 2008; Lahiri, Ramanuj ... Summary Objective The immune-mediated events that precipitate erythema nodosum leprosum (ENL) are not well understood. One component may be the complexing of antibody with antigens released from infected macrophages, the activation of complement and the subsequent local ...
Assessment of subclinical leprosy infection through the measurement of PGL-1 antibody levels in residents of a former leprosy colony in Thailand.(phenolic glycolipid-I )(Clinical report)
Sep 01, 2008; Kampirapap, Kowit ... Summary Objectives To investigate the hypothesis that there is continuing subclinical M. leprae infection, contributing to ongoing transmission of leprosy in Phra-Pradaeng Colony. Design A sero-epidemiological survey was carried out in Phra-Pradaeng Colony, Thailand between May ...
Relapses in multibacillary leprosy patients after Multidrug therapy.(CASE REPORT)(Case study)
Sep 01, 2008; Poojabylaiah, Mitranna ... Summary Objectives To determine the magnitude of relapses in multibacillary leprosy patients after multi-drug therapy and to determine the factors influencing the relapse. Design A retrospective study pertaining to multibacillary leprosy patients treated with MBMDT as per WHO ...
Surgical treatment of three cases of plantar foot ulceration in leprosy.(CASE REPORT)(Case study)
Sep 01, 2008; Vieira, Raquel ... Summary Neurophatic foot ulceration (NFU) is a common problem in leprosy patients. Three cases of NFU, who did not respond to conservative measures, were treated with orthopaedic surgery. The purpose of the treatment was, by using different approaches, the reduction of bone hyper pressure ...
Two microbiological relapses in a patient with lepromatous leprosy.(CASE REPORT)(Case study)
Sep 01, 2008; Chakma, J.K. ... Summary A lepromatous patient treated with dapsone in the pre-MDT era to the point of smear negativity (> 6 years), relapsed 5 years after stopping treatment. He was then put on WHO-MDT for multibacillary (MB) leprosy, and was treated again; he had negative slit skin smears (3 years). He ...
Schwann cell invasion by M. Leprae: the probable Trojan horse.(Mycobacterium leprae)(Clinical report)
Sep 01, 2008; Eapen, Bell Raj ... The ability of Mycobacterium leprae to invade and sustain inside Schwann cells is vital in the pathogenesis of leprosy. M. leprae has the capacity to induce Schwann cell proliferation thereby providing enough host cells for bacterial propagation. It also has the ability to cause extensive ...
Can urban health posts manage leprosy detection and treatment after integration with general health services?--A study in Bombay.(Clinical report)
Sep 01, 2008; Ganapati, R. ... Bombay Leprosy Project (BLP) covers an urban population of 2 million comprising mainly of slums including Dharavi, the biggest in Asia. We present our experience in BLP after integration of leprosy management into General Health Care (GHC) System. The leprosy programme was ...
Can primary health centres offer care to the leprosy-disabled after integration with general health services?--A study in rural India.(Clinical report)
Sep 01, 2008; Ganapati, R. ... We have earlier reported on the disease burden caused by leprosy disabilities in Shahapur, a 'taluka' (sub-unit of a district) situated about 100 km from the metropolis of Bombay. (l,2) In the population of 2,78,524, a total of 286 patients with disabilities were identified by engaging ...
Making HIV AIDS Outreach efforts more effective: including people with a disability: high-level training workshop on HIV/AIDS and Disability 19th to 20th November 2008.
Sep 01, 2008 ... The number of disabled people worldwide is considerable--the figure of 650 million is often quoted. People with a disability and their families also account for 20% of the world's poorest people. But so far most HIV/AIDS programmes are not accessible to people with disabilities. ...
Community based rehabilitation (CBR) course.(ANNOUNCEMENT)
Sep 01, 2008 ... Increasingly, rehabilitation and prevention of disability takes place in the community with the active involvement and participation of the community. CBR advocates appropriate technology, the formation of self-help groups, and microfinance business training. These activities aim to ...
Rehabilitation and prevention of disability (RPOD) course.(ANNOUNCEMENT)
Sep 01, 2008 ... The major focus of this course is the prevention and management of leprosy-related disability, however the course also addresses general disability principles that can be related to other causes such as diabetes, filariasis, Buruli ulcer and nerve injury. Course outline ...
