Recently added articles from Journal of Electrocardiology:
The role of continuous monitoring in a 24/7 telecardiology consultation service-a feasibility study
Nov 01, 2009; Nikus, Kjell; Lähteenmäki, Jaakko; Lehto, Pasi; Eskola, Markku ... Abstract Today's coronary care unit patients include those with complicated and uncomplicated myocardial infarction, decompensated heart failure and frank cardiogenic shock, severe valvular heart disease, high-grade conduction disturbances, and incessant ventricular arrhythmias. Increasingly in ...
The Guardian: an implantable system for chronic ambulatory monitoring of acute myocardial infarction
Nov 01, 2009; Hopenfeld, Bruce; John, M Sasha; Fischell, David R; Medeiros, Paulo; Guimarães, Hélio P; Piegas, Leopoldo S ... Abstract The AngelMed Guardian is an implantable medical device that records cardiac data and detects ischemic events using a standard pacemaker intracardiac lead positioned in the right ventricular apex. The Guardian has been implanted in 55 people in the United States and Brazil and is ...
From ST-elevation myocardial infarction to ST elevation with no myocardial infarction-review and overview of a new horizon of computerized electrocardiographic ischemia detection using high-fidelity implantable devices
Nov 01, 2009; Krucoff, Mitchell W ... Abstract ST-segment elevation is the clinical hallmark of ST-elevation myocardial infarction; however pafhophysiologically ST elevation occurs in association with acute coronary occlusion long before any myocardial necrosis occurs, for example, with no myocardial infarction (MI). The clinical ...
Cardiac regulation and electrocardiographic factors contributing to the measurement of repolarization variability
Nov 01, 2009; Couderc, Jean-Philippe ... Abstract Cellular and macroelectrical instability within the heart ventricles during repolarization is described as a potential triggering mechanism of life-threatening arrhythmias. Although this phenomenon was observed in animal and in vitro studies, significant efforts have been put into the ...
24-Hour QT variability in heart failure*
Nov 01, 2009; Dobson, Craig P; La Rovere, Maria Teresa; Olsen, Cara; Berardinangeli, Marino; Veniani, Marco; Midi, Paolo; Tavazzi, Luigi; Haigney, Mark ... Abstract Background: Previous studies have shown that increased temporal variability of repolarization, as reflected by QT interval variability measured for 10 minutes, predicted spontaneous ventricular arrhythmias in implantable cardioverter defribrillator patients, but it is unclear how these ...
Intracardiac QT variability in patients with structural heart disease on class III antiarrhythmic drugs
Nov 01, 2009; Tereshchenko, Larisa G; Fetics, Barry J; Berger, Ronald D ... Abstract We previously showed that increased intracardiac repolarization lability predicts life-threatening ventricular arrhythmias in patients with structural heart disease. Patients with structural heart disease frequently take antiarrhythmic drugs (AADs), which directly affect repolarization ....
The many faces of repolarization instability: which one is prognostic?
Nov 01, 2009; Shusterman, Vladimir; Lampert, Rachel; London, Barry ... Abstract Instabilities of the STT segment's magnitude, and particularly the 0.5 beat/cycle oscillations (T-wave alternans, or TWA), have been linked to the heightened risk of ventricular tachyarrhythmias (VTA) and sudden cardiac death (SCD). During the last decade theoretical, experimental and ...
Development of a toolbox for electrocardiogram-based interpretation of atrial fibrillation
Nov 01, 2009; Abächerli, Roger; Leber, Remo; Lemay, Mathieu; Vesin, Jean-Marc; van Oosterom, Adriaan; Schmid, Hans-Jakob; Kappenberger, Lukas ... Abstract Background: Atrial fibrillation (AF) develops as a consequence of an underlying heart disease such as fibrosis, inflammation, hyperthyroidism, elevated intra-atrial pressures, and/or atrial dilatation. The arrhythmia is initiated by, or depends on, ectopic focal activity. Autonomic ...
Improvements in atrial fibrillation detection for real-time monitoring
Nov 01, 2009; Babaeizadeh, Saeed; Gregg, Richard E; Helfenbein, Eric D; Lindauer, James M; Zhou, Sophia H ... Abstract Electrocardiographic (ECG) monitoring plays an important role in the management of patients with atrial fibrillation (AF). Automated real-time AF detection algorithm is an integral part of ECG monitoring during AF therapy. Before and after antiarrhythmic drug therapy and surgical ...
Changes in the frequency spectrum, the P-P interval, and the bispectral index during ventricular fibrillation are physiologic indicators of ventricular fibrillation duration
Nov 01, 2009; Di Maio, Rebecca; Allen, John D; Navarro, Cesar; Darragh, Karen; Anderson, John M C; Adgey, A A Jennifer ... Abstract The 3-phase time-sensitive model by Weisfeldt and Becker in 2002 has resulted in a redirection of efforts toward developing treatment algorithms specific to each phase of cardiac arrest. In this study, a number of physiologic indicators of ventricular fibrillation (VF) duration were ...
Identify drug-induced T wave morphology changes by a cell-to-electrocardiogram model and validation with clinical trial data
Nov 01, 2009; Xue, Joel; Gao, Weihua; Chen, Yao; Han, Xiaodong ... Abstract Background: Increase of repolarization heterogeneity has been identified as a major factor for drug-induced arrhythmia event like torsade de pointes. In recent years, there have been quite a few efforts for studying T wave morphology changes, hoping to identify more sensitive ...
Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation*
Nov 01, 2009; Antzelevitch, Charles; Burashnikov, Alexander ... Abstract Pharmacological management of atrial fibrillation (AF) remains an important unmet medical need. Because available drugs for rhythm control of AF are often associated with a significant risk for development of ventricular arrhythmias or extracardiac toxicity, recent drug development has ...
Relationship between extracellular T-wave height, T-wave alternans amplitude, and tissue action potential alternans: a 1-dimensional computer modeling study*
Nov 01, 2009; Doshi, Ashish N; Idriss, Salim F ... Abstract T-wave alternans (TWA) is a useful marker of cardiac instability, but not much is known about the factors that affect its measurement, such as electrode placement. We used a 1 -dimensional myocardial fiber computer model of alternans to investigate the effect of electrode position on ...
The prognostic value of the Tpeak-Tend interval in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction*
Nov 01, 2009; Haarmark, Christian; Hansen, Peter R; Vedel-Larsen, Esben; Pedersen, Sune Haahr; Graff, Claus; Andersen, Mads P; Toft, Egon; Wang, Fan; Struijk, Johannes J; Kanters, Jørgen K ... Abstract Introduction: The Tpeak-Tend interval (TpTe) has been linked to increased arrhythmic risk. TpTe was investigated before and after primary percutaneous coronary intervention (pPCI) in patients with ST-segment elevation myocardial infarction (STEMI). Method: Patients with ...
Right ventricular apical lead position is associated with prolonged signal-averaged P-wave duration
Nov 01, 2009; Maraschiello, Mark A; Redfearn, Damian P; Baranchuk, Adrian M; Simpson, Christopher S ... Abstract Aim: The study aimed to determine if right ventricular apical pacing is associated with adverse change in atrial substrate compared with right ventricular septal pacing. Methods: Patients with septal leads and dual-chamber devices with more than 3 months of follow-up and 70% or ...
New material for implantable cardiac leads
Nov 01, 2009; Lobodzinski, S Suave; MD, Michael ... Abstract Cardiac function management devices, including implantable pacemakers and implantable defibrillators, include at least 1 cardiac lead having an electrode for making contact with a portion of the heart. It has been previously shown that the braided multifilament wire electrodes have a ...
Meet the challenge of high-pass filter and ST-segment requirements with a DC-coupled digital electrocardiogram amplifier
Nov 01, 2009; Abächerli, Roger; Schmid, Hans-Jakob ... Abstract Background: The high-pass filter (HPF) in an electrocardiogram (ECG) amplifier can distort the ST segment required for ischemia interpretation. Therefore, the current standards and guidelines require -3 dB for monitoring and -0.9 dB for diagnostic purposes at 0.67 Hz. In addition, a ...
Improving sensing and detection performance in subcutaneous monitors
Nov 01, 2009; van Dam, Peter; van Groeningen, Chris; Houben, Richard P M; Hampton, David R ... Abstract Implantable loop recorders (ILRs) are used for continuous assessment of patients at risk for syncope and arrhythmia. Device accuracy depends on appropriate sensing of the patient's electrocardiogram (ECG) signal. However, current methods for sensing cardiac electrical activity rely on ...
Serial evaluation of electrocardiographic left ventricular hypertrophy for prediction of risk in hypertensive patients*
Nov 01, 2009; Okin, Peter M ... Abstract Background: Although the presence and severity of electrocardiographic (ECG) left ventricular hypertrophy (LVH) have been associated with an increased risk of cardiovascular (CV) morbidity and mortality, the relationship of regression of ECG LVH during antihypertensive therapy to CV ...
The electrocardiogram in left ventricular hypertrophy: past and future
Nov 01, 2009; Estes, E Harvey; Jackson, Kevin P ... Abstract The electrocardiographic diagnosis of left ventricular hypertrophy (LVH) has been centered on improving the diagnostic sensitivity and specificity of the method, using criteria whose precise relationship to increased left ventricular mass are not established. Although the ...
